A Level Organic Chemistry: Reaction mechanisms - acid/acyl chloride plus alcohols
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Doc Brown's Chemistry Advanced Level Pre-University Chemistry Revision Study Notes for UK KS5 A/AS GCE IB advanced level organic chemistry students US K12 grade 11 grade 12 organic chemistry
GCE A Level Revision Notes PART 10 Summary of organic reaction mechanisms - A mechanistic introduction to organic chemistry and explanations of different types of organic reactions
10.7 Reaction of acid/acyl chlorides with alcohols
Examples are explained of the organic chemistry mechanisms for acid/acyl chlorides undergoing nucleophilic addition and elimination reactions. They are described with diagrams and full explanation revision notes. Esterification with alcohols to give an ester. The revision notes include full diagrams and explanation of the mechanisms and the 'molecular' equation and reaction conditions are also explained.
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10.7 CARBOXYLIC ACIDS and DERIVATIVES – Acyl/acid chlorides
10.7.1 Introduction to acid chloride/acyl chloride activity
Only acid chloride reactions are considered at the moment and the high reactivity of acyl chlorides is towards nucleophilic attack is due to the highly polarised situation of the carbon–oxygen/chlorine bonds i.e.
10.7.3 Acyl chloride esterification by nucleophilic addition–elimination
The organic synthesis of esters from the reaction of acid/acyl chloride with alcohols
mechanism 15 – nucleophilic addition–elimination reaction for the esterification of an acyl chloride
keywords phrases: reaction conditions formula intermediates organic chemistry reaction mechanisms nucleophilic addition elimination HCl R–COCl + R'OH ==> R–COOR' + HCl
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COMPLETE MECHANISM and Organic Synthesis INDEX (so far!)
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